c-Myb redefines the hierarchy of stem-like T cells
Published:
Akin to adult stem cells, precursor exhausted T cells are hierarchically organized, with long-lived CD62L+ stem-like T cells at the apex of the system. The transcription factor c-Myb controls the formation, maintenance and therapeutic function of these cells, with important implications for their clinical utilization.
Recommended citation: Heuser C, Gattinoni L. Nat Immunol. Oct 3, 2022 23(10): 1405-1407
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